• Digital Dentistry
  • Data Security
  • Implants
  • Catapult Education
  • Digital Imaging
  • Laser Dentistry
  • Restorative Dentistry
  • Cosmetic Dentistry
  • Periodontics
  • Oral Care
  • Cement and Adhesives
  • Equipment & Supplies
  • Ergonomics
  • Products
  • Dentures
  • Infection Control
  • Orthodontics
  • Technology
  • Techniques
  • Materials
  • Emerging Research
  • Pediatric Dentistry
  • Endodontics
  • Oral-Systemic Health

Poor oral health linked to higher mortality rate in patients with kidney disease


New findings from the University of Birmingham show that patients with chronic kidney disease patients and periodontitis have a higher mortality rate than those with chronic kidney disease alone.

New findings from the University of Birmingham show that patients with chronic kidney disease patients and periodontitis have a higher mortality rate than those with chronic kidney disease alone.

The research adds to the growing evidence for poor oral health being associated with other chronic diseases.

More emerging research: Study finds oral bacteria linked to risk of stroke

Data from 13,734 participants in the US-based Third National Health and Nutrition Examination Survey (NHANES III) were analyzed to show that individuals with both periodontitis and chronic kidney disease had an all-cause mortality rate of 41 percent at 10 years, compared to 32 percent for those with chronic kidney disease alone.

To put this into context, the increase in 10-year mortality associated with diabetes in patients with chronic kidney disease, independent of periodontitis, is from 32 percent in non-diabetics to 43 percent in diabetics.

Periodontitis is a chronic non-communicable disease, and in its most severe form is the sixth most prevalent human disease, affecting 11.2 percent of the world's population.

Chronic non-communicable diseases, such as kidney disease, are increasingly prevalent, partly as a result of an aging population and an increase in sedentary lifestyles and refined diets. Their impact upon the global disease burden and healthcare economy is significant, and evidence suggests that 92 percent of older adults have at least one chronic disease.

More emerging research: Dental care linked to risk of respiratory infections in ICU patients

Professor Iain Chapple, from the University of Birmingham, explained, "It's important to note that oral health isn't just about teeth. The mouth is the doorway to the body, rather than a separate organ, and is the access point for bacteria to enter the bloodstream via the gums. A lot of people with gum disease aren't aware of it, perhaps they just have blood in their spit after brushing teeth, but this unchecked damage to gums then becomes a high risk area for the rest of the body."

Mr. Praveen Sharma, a co-author of the study, added, "We are just beginning to scratch the surface of the interplay between gum disease and other chronic diseases; whether that be kidney disease, diabetes or cardiovascular disease. Knowing the heightened risk that gum disease presents to patients who already have another chronic disease tells us that oral health has a significant role to play in improving patient outcomes."

Following this paper, the team are now investigating the link between gum and kidney disease further, to identify if the association is causal, and if so, whether treating gum disease and maintaining oral health can improve the overall health of patients with kidney disease.

Trending research: Is there a link between Alzheimer's and oral health?

Professor Chapple said, "It may be that the diagnosis of gum disease can provide an opportunity early detection of other problems, whereby dental professionals could adopt a targeted, risk-based approach to screening for other chronic diseases."

The full study, “Association between periodontitis and mortality in stage 3-5 chronic kidney disease: NHANES III and linked mortality study,” was published in the Journal of Clinical Periodontology.


This post was adapted from materials provided by the University of Birmingham. It has been edited for content and length.

Related Videos
2024 Dental Products Report Spring Selection Bracket Reveal Video
Addressing Unmet Needs in Early Childhood Oral Care - an interview with Ashlet Lerman, DDS
2024 Chicago Dental Society Midwinter Meeting – Interview with Peter Maroon, business development and sales lead at Spectrum Solutions® on the new salivary diagnostic test, SimplyPERIO.
CDS 2024: What's New at TAG University? with Andrew De la Rosa, DMD
CDS 2024: Breaking Down Barriers to Care with Eric Kukucka, DD
GNYDM23 Product Focus: CandidPro with Kristin Lange, VP of Sales at Candid
The Connected Future of Dental CAD/CAM with Max Milz
Greater New York Dental Meeting 2023 – Interview with Emily Boge, EdD, RDH, CDA, FAADH, FADHA - Paradise Dental Technologies
Greater New York Dental Meeting 2023 – Interview with Daniel Weinstein from Lura Health
Greater New York Dental Meeting 2023 – Interview with Anthony P Urbanek, DDS, MS, MD
Related Content
© 2024 MJH Life Sciences

All rights reserved.